If entrepreneur Jim Plante and his team at Klotho Therapeutics are successful, they will help people with the genetic mutation for polycystic kidney disease delay onset of symptoms until a very late age or prevent the occurrence altogether. Their work involves a gene known as Klotho that is a hormone. Klotho has many functions in the body, and it appears to help prevent degenerative diseases through chemical processes. The body produces much less of this hormone by middle age, and degenerative diseases become markedly more common as people get older.
About Polycystic Kidney Disease
People with this disease develop large numbers of cysts in the kidneys that eventually causes the organs to lose their functional ability. This is a life-threatening consequence because kidneys are crucial for filtering waste from the blood and preventing toxins from building up to lethal levels. When chronic kidney failure develops, the person must receive regular …
Malignant Mesothelioma is a rare form of cancer that requires highly specialized management. Like most cancers, three treatment options coexist – surgery, chemotherapy, and radiotherapy. This article outlines everything a person needs to know concerning mesothelioma treatment.
Choice of treatment
The choice of treatment depends on the:
- Type of symptoms observed
- General condition of the patient
- Patient’s family and medical background
Surgery is used only at a very early stage of the disease, and this is rare. Two surgical approaches are possible: a pleurectomy-decortication and an extra-pleural pleuro-pneumonectomy. In both cases, the goal is to eliminate as much of the tumor as possible.
A pleurectomy-decortication is the least radical of the two interventions. It only involves the removal of the pleura without removing the lung. The advantage of this procedure is that it offers a generally faster …
Benign mesothelioma and malignant mesothelioma are very serious issues, both in their own right. For instance, the benign type is very rare. Some benign mesotheliomas consist of adenomatoid tumors and benign cystic mesothelioma.
The most common malignant type is a rare but very aggressive form of neoplasia. Malignant mesothelioma is distinguished by the type of malignant cell present. Pleural Mesothelioma is a malignant form of this disease.
Symptoms of pleural mesothelioma
The signs and symptoms of pleural mesothelioma may be:
- Chest pain (mild to severe)
- Shortness of breath, even at rest
- Nodules on the skin and on the thorax
- A persistent cough (mild to severe)
Some of these symptoms are very serious, even when they are alone. However, together, they can be deadly if ignored. Below are the different cell types of mesothelioma.…
Pleural Mesothelioma is an uncommon type of cancer but is not uncommon in people exposed to asbestos. These men and women have a risk of more than 1,000 times higher to develop mesothelial than anyone not exposed. The risk doubles when the person exposed to asbestos is a smoker because tobacco stimulates macrophages that have an important role in the development of mesothelioma.
Exposure to asbestos can be direct or indirect. Direct exposure occurs when an individual comes in contact with asbestos fibers, for example:
- People who work in asbestos mines
- Scrap dealers and mechanics who deal with brakes and clutches on vehicles
Indirect exposure occurs when people:
- Come in contact indirectly with asbestos (for example, they live or spend time in buildings that have asbestos-used elements: pipes, roofs, etc.)
- Are in contact with people exposed directly to asbestos, for example, family members or
The main reason people get mesothelioma is by the inhalation of asbestos. Finding the right Mesothelioma Treatment is a must. However, there are other effects to be concerned about.
For instance, asbestosis is the formation of scar tissue or fibrosis of the lung due to exposure and lung cancer is a carcinoma that develops in the lung tissue. Mesothelioma is very different from these. It should not be confused with lung carcinoma or asbestosis.
Mesothelioma is difficult to diagnose because the symptoms are similar to other more common disorders, such as:
The doctor, after having examined the complete medical file of the patient, may order other tests if he or she feels mesothelioma is a possibility. The best way to diagnose a case of mesothelioma is to perform additional tests, for example:
- A chest X-ray. In case of mesothelioma, the X-ray